Apparently, as you rack up the difficulty in solo mode, there's going to be monsters that might hit around 3k as normal hit. I hadn't gotten around circumventing that obstacle, but the charges/skills that do an estimate of 10k is quite a whopper! I hadn't gotten maxed up ranking characters at the moment. I suppose that a (or even several) nuking character or lethal hit might work, however, that's in a differently situation, particularly for the 1 million+ health.
For now, I just want some general tips when facing off charges/skills that deal a 10k estimate. I can't always predict it. Figures that if there is really a way to recuperate from the damage or even protect against it. Even then, the cool-down count would leave the party in the open. I suspect that solos might require a lot of reviving items. This is where the real monetary investment payout might come in. Then again, I also see a lot of high ranking players in raid modes, trying to get as much honors as possible.